Conclusion and Implications
The systematic evaluation of diastolic function by echocardiography as established by the current guidelines enables a more accurate identification of cardiac abnormalities in at risk patients at an earlier and hopefully reversible stage of their disease. Our work shows that IFG is associated to LVDD among middle age adults independently of numerous factors, including concentric remodeling, LVH and obesity. These findings support evaluation of diastolic function in subjects with IFG for possible early cardiac involvement in dysglycemic process. Future prospective longitudinal studies are required to assess long-term prognosis and the reversibility of LVDD through life style modification, drug treatment and other medical interventions in these patients.